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1,2-(Bis)trifluoromethylation of Alkynes: A One-Step Reaction to Install an Underutilized Functional Group
Modifying the electronic properties of olefins represents the quintessential approach to tuning alkene reactivity. In this context, the exploration of trifluoromethyl groups as divergent electronic modifiers has not been considered. Here, we describe a copper-mediated 1,2-(bis)trifluoromethylation o...
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| Pubblicato in: | Angew Chem Int Ed Engl |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7065645/ https://ncbi.nlm.nih.gov/pubmed/31206968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201905247 |
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