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mTOR Blockade by Rapamycin in Spondyloarthritis: Impact on Inflammation and New Bone Formation in vitro and in vivo

Introduction: Spondyloarthritis (SpA) is characterized by inflammation, articular bone erosions and pathologic new bone formation. Targeting TNFα or IL-17A with current available therapies reduces inflammation in SpA, however, treatment of the bone pathology in SpA remains an unmet clinical need. Ac...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Chen, Sijia, van Tok, Melissa N., Knaup, Véronique L., Kraal, Lianne, Pots, Désiree, Bartels, Lina, Gravallese, Ellen M., Taurog, Joel D., van de Sande, Marleen, van Duivenvoorde, Leonie M., Baeten, Dominique L.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065603/
https://ncbi.nlm.nih.gov/pubmed/32194539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02344
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