The Initiation, but Not the Persistence, of Experimental Spondyloarthritis Is Dependent on Interleukin-23 Signaling

IL-17A is a central driver of spondyloarthritis (SpA), its production was originally proposed to be IL-23 dependent. Emerging preclinical and clinical evidence suggests, however, that IL-17A and IL-23 have a partially overlapping but distinct biology. We aimed to assess the extent to which IL-17A-dr...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: van Tok, Melissa N., Na, Songqing, Lao, Christopher R., Alvi, Marina, Pots, Desirée, van de Sande, Marleen G. H., Taurog, Joel D., Sedgwick, Jonathon D., Baeten, Dominique L., van Duivenvoorde, Leonie M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046377/
https://ncbi.nlm.nih.gov/pubmed/30038617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01550
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