The Initiation, but Not the Persistence, of Experimental Spondyloarthritis Is Dependent on Interleukin-23 Signaling

IL-17A is a central driver of spondyloarthritis (SpA), its production was originally proposed to be IL-23 dependent. Emerging preclinical and clinical evidence suggests, however, that IL-17A and IL-23 have a partially overlapping but distinct biology. We aimed to assess the extent to which IL-17A-dr...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: van Tok, Melissa N., Na, Songqing, Lao, Christopher R., Alvi, Marina, Pots, Desirée, van de Sande, Marleen G. H., Taurog, Joel D., Sedgwick, Jonathon D., Baeten, Dominique L., van Duivenvoorde, Leonie M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046377/
https://ncbi.nlm.nih.gov/pubmed/30038617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01550
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