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Regulatory T cells and co‐evolution of allele‐specific MHC recognition by the TCR
What is the evolutionary mechanism for the TCR‐MHC‐conserved interaction? We extend Dembic's model (Dembic Z. In, Scand J Immunol e12806, 2019) of thymus positive selection for high‐avidity anti–self‐MHC Tregs among double (CD4 + CD8+)‐positive (DP) developing thymocytes. This model is based on...
Shranjeno v:
| izdano v: | Scand J Immunol |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7064991/ https://ncbi.nlm.nih.gov/pubmed/31793005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/sji.12853 |
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