Maternal Broadly Neutralizing Antibodies Can Select for Neutralization-Resistant, Infant-Transmitted/Founder HIV Variants

Each year, >180,000 infants become infected via mother-to-child transmission (MTCT) of HIV despite the availability of effective maternal antiretroviral treatments, underlining the need for a maternal HIV vaccine. We characterized 224 maternal HIV envelope (Env)-specific IgG monoclonal antibodies...

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Bibliografske podrobnosti
izdano v:mBio
Main Authors: Martinez, David R., Tu, Joshua J., Kumar, Amit, Mangold, Jesse F., Mangan, Riley J., Goswami, Ria, Giorgi, Elena E., Chen, Juilin, Mengual, Michael, Douglas, Ayooluwa O., Heimsath, Holly, Saunders, Kevin O., Nicely, Nathan I., Eudailey, Joshua, Hernandez, Giovanna, Morgan-Asiedu, Papa Kwadwo, Wiehe, Kevin, Haynes, Barton F., Moody, M. Anthony, LaBranche, Celia, Montefiori, David C., Gao, Feng, Permar, Sallie R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064758/
https://ncbi.nlm.nih.gov/pubmed/32156815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00176-20
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