HIV transmitted/founder vaccines elicit autologous tier 2 neutralizing antibodies for the CD4 binding site

Here we report the construction, antigenicity and initial immunogenicity testing of DNA and modified vaccinia Ankara (MVA) vaccines expressing virus-like particles (VLPs) displaying sequential clade C Envelopes (Envs) that co-evolved with the elicitation of broadly neutralizing antibodies (bnAbs) to...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: McCurley, Nathanael P., Domi, Arban, Basu, Rahul, Saunders, Kevin O., LaBranche, Celia C., Montefiori, David C., Haynes, Barton F., Robinson, Harriet L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636061/
https://ncbi.nlm.nih.gov/pubmed/29020058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177863
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