A Zika Vaccine Targeting NS1 Protein Protects Immunocompetent Adult Mice in a Lethal Challenge Model

Zika virus (ZIKV) is a mosquito-borne flavivirus that has rapidly extended its geographic range around the world. Its association with abnormal fetal brain development, sexual transmission, and lack of a preventive vaccine have constituted a global health concern. Designing a safe and effective vacc...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Brault, Aaron C., Domi, Arban, McDonald, Erin M., Talmi-Frank, Dalit, McCurley, Nathanael, Basu, Rahul, Robinson, Harriet L., Hellerstein, Michael, Duggal, Nisha K., Bowen, Richard A., Guirakhoo, Farshad
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677088/
https://ncbi.nlm.nih.gov/pubmed/29116169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15039-8
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