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Identification and functional characterisation of N-linked glycosylation of the orphan G protein-coupled receptor Gpr176

G-protein-coupled receptors (GPCRs) are important drug targets with diverse therapeutic applications. However, there are still more than a hundred orphan GPCRs, whose protein functions and biochemical features remain unidentified. Gpr176 encodes a class-A orphan GPCR that has a role in circadian clo...

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發表在:Sci Rep
Main Authors: Wang, Tianyu, Nakagawa, Shumpei, Miyake, Takahito, Setsu, Genzui, Kunisue, Sumihiro, Goto, Kaoru, Hirasawa, Akira, Okamura, Hitoshi, Yamaguchi, Yoshiaki, Doi, Masao
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064540/
https://ncbi.nlm.nih.gov/pubmed/32157140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61370-y
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