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Angiotensin II Triggers Expression of the Adrenal Gland Zona Glomerulosa-Specific 3β-Hydroxysteroid Dehydrogenase Isoenzyme through De Novo Protein Synthesis of the Orphan Nuclear Receptors NGFIB and NURR1

The 3β-hydroxysteroid dehydrogenase (3β-HSD) is an enzyme crucial for steroid synthesis. Two different 3β-HSD isoforms exist in humans. Classically, HSD3B2 was considered the principal isoform present in the adrenal. However, we recently showed that the alternative isoform, HSD3B1, is expressed spec...

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Detalhes bibliográficos
Main Authors: Ota, Takumi, Doi, Masao, Yamazaki, Fumiyoshi, Yarimizu, Daisuke, Okada, Kazuki, Murai, Iori, Hayashi, Hida, Kunisue, Sumihiro, Nakagawa, Yuuki, Okamura, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187706/
https://ncbi.nlm.nih.gov/pubmed/25092869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00852-14
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