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Nutrient Signaling and Lysosome Positioning Crosstalk Through a Multifunctional Protein, Folliculin

FLCN was identified as the gene responsible for Birt-Hogg-Dubé (BHD) syndrome, a hereditary syndrome associated with the appearance of familiar renal oncocytomas. Most mutations affecting FLCN result in the truncation of the protein, and therefore loss of its associated functions, as typical for a t...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: de Martín Garrido, Natàlia, Aylett, Christopher H. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063858/
https://ncbi.nlm.nih.gov/pubmed/32195250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00108
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