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Folliculin directs the formation of a Rab34–RILP complex to control the nutrient‐dependent dynamic distribution of lysosomes

The spatial distribution of lysosomes is important for their function and is, in part, controlled by cellular nutrient status. Here, we show that the lysosome associated Birt–Hoge–Dubé (BHD) syndrome renal tumour suppressor folliculin (FLCN) regulates this process. FLCN promotes the peri‐nuclear clu...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Starling, Georgina P, Yip, Yan Y, Sanger, Anneri, Morton, Penny E, Eden, Emily R, Dodding, Mark P
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893818/
https://ncbi.nlm.nih.gov/pubmed/27113757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201541382
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