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Folliculin: A Regulator of Transcription Through AMPK and mTOR Signaling Pathways

Folliculin (FLCN) is a tumor suppressor gene responsible for the inherited Birt-Hogg-Dubé (BHD) syndrome, which affects kidneys, skin and lungs. FLCN is a highly conserved protein that forms a complex with folliculin interacting proteins 1 and 2 (FNIP1/2). Although its sequence does not show homolog...

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Pubblicato in:Front Cell Dev Biol
Autori principali: Ramirez Reyes, Josué M. J., Cuesta, Rafael, Pause, Arnim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107286/
https://ncbi.nlm.nih.gov/pubmed/33981707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.667311
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