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The Irving-William series and the 2-His-1-carboxylate facial triad: A thermodynamic study of Mn(2+), Fe(2+), and Co(2+) binding to taurine/α-ketoglutarate dioxygenase (TauD)
Taurine/α-ketoglutarate (αKG) dioxygenase (TauD) is a nonheme Fe(2+) and αKG dependent metalloenzyme, which catalyzes the hydroxylation of taurine eventually leading to sulfite production in Escherichia coli. The metal-dependent active site in TauD is formed by two histidine and an aspartate side-ch...
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| Publicado no: | J Biol Inorg Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7063563/ https://ncbi.nlm.nih.gov/pubmed/29923040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-018-1574-4 |
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