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A Calorimetric Assessment of Fe(2+) Binding to α-Ketoglutarate/Taurine Dioxygenase: Ironing Out the Energetics of Metal Coordination by the 2-His-1-Carboxylate Facial Triad

The thermodynamic properties of Fe(2+) binding to the 2-His-1-carboxylate facial triad in α-ketoglutarate/taurine dioxygenase (TauD) were explored using isothermal titration calorimetry. Direct titrations of Fe(2+) into TauD and chelation experiments involving the titration of ethylenediaminetetraac...

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Detalhes bibliográficos
Publicado no:Inorg Chem
Main Authors: Henderson, Kate L., Müller, Tina A., Hausinger, Robert P., Emerson, Joseph P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453723/
https://ncbi.nlm.nih.gov/pubmed/25668068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic502881q
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