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Gene therapy and genome editing for primary immunodeficiency diseases

In past two decades the gene therapy using genetic modified autologous hematopoietic stem cells (HSCs) transduced with the viral vector has become a promising alternative option for treating primary immunodeficiency diseases (PIDs). Despite of some pitfalls at early stage clinical trials, the field...

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Bibliografiske detaljer
Udgivet i:Genes Dis
Main Authors: Zhang, Zhi-Yong, Thrasher, Adrian J., Zhang, Fang
Format: Artigo
Sprog:Inglês
Udgivet: Chongqing Medical University 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063425/
https://ncbi.nlm.nih.gov/pubmed/32181274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2019.07.007
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