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Concise Review: Lessons Learned From Clinical Trials of Gene Therapy in Monogenic Immunodeficiency Diseases

Thirty years ago, retroviral transfer of genetic material into hematopoietic stem and progenitor cells (HSC/Ps) led to predictions that this technology would transform modern medicine [Nature 1983;305:556–558; Nature 1984;310:476–480]. Studies in several immunodeficiency diseases in the past 15 year...

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Detalhes bibliográficos
Main Authors: Williams, David A., Thrasher, Adrian J.
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006494/
https://ncbi.nlm.nih.gov/pubmed/24682287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2013-0206
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