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Gene therapy and genome editing for primary immunodeficiency diseases

In past two decades the gene therapy using genetic modified autologous hematopoietic stem cells (HSCs) transduced with the viral vector has become a promising alternative option for treating primary immunodeficiency diseases (PIDs). Despite of some pitfalls at early stage clinical trials, the field...

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Detalhes bibliográficos
Publicado no:Genes Dis
Main Authors: Zhang, Zhi-Yong, Thrasher, Adrian J., Zhang, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Chongqing Medical University 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063425/
https://ncbi.nlm.nih.gov/pubmed/32181274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2019.07.007
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