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High-Throughput Small Molecule Screen Identifies Modulators of Mitochondrial Function in Neurons
We developed a high-throughput assay for modulators of mitochondrial function in neurons measuring inner mitochondrial membrane potential (ΔΨ(m)) and ATP production. The assay was used to screen a library of small molecules, which led to the identification of structural/functional classes of mitocho...
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| Veröffentlicht in: | iScience |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7063260/ https://ncbi.nlm.nih.gov/pubmed/32146326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100931 |
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