Prostaglandin E(2) Induces MIR675-5p to Promote Colorectal Tumor Metastasis via Modulation of p53 Expression

BACKGROUND & AIMS: Prostaglandin E(2) (PGE(2)) promotes colorectal tumor formation and progression by unknown mechanisms. We sought to identify microRNAs (miRNAs) might mediate the effects of PGE(2) on colorectal cancer (CRC) development. METHODS: We incubated LS174T colorectal cancer cells with...

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Publicado en:Gastroenterology
Main Authors: Cen, Bo, Lang, Jessica D., Du, Yuchen, Wei, Jie, Xiong, Ying, Bradley, Norma, Wang, Dingzhi, DuBois, Raymond N.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062589/
https://ncbi.nlm.nih.gov/pubmed/31734182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.11.013
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