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Prostaglandin E(2) Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice

BACKGROUND & AIMS: Inflammation may contribute to formation, maintenance, and expansion of cancer stem cells (CSCs), which have the capacity for self-renewal, differentiation, and resistance to cytotoxic agents. We investigated the effects of the inflammatory mediator prostaglandin E(2) (PGE(2))...

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Bibliografische gegevens
Gepubliceerd in:Gastroenterology
Hoofdauteurs: Wang, Dingzhi, Fu, Lingchen, Sun, Haiyan, Guo, Lixia, DuBois, Raymond N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762503/
https://ncbi.nlm.nih.gov/pubmed/26261008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.07.064
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