Derivation of trophoblast stem cells from naïve human pluripotent stem cells

Naïve human pluripotent stem cells (hPSCs) provide a unique experimental platform of cell fate decisions during pre-implantation development, but their lineage potential remains incompletely characterized. As naïve hPSCs share transcriptional and epigenomic signatures with trophoblast cells, it has...

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Pubblicato in:eLife
Autori principali: Dong, Chen, Beltcheva, Mariana, Gontarz, Paul, Zhang, Bo, Popli, Pooja, Fischer, Laura A, Khan, Shafqat A, Park, Kyoung-mi, Yoon, Eun-Ja, Xing, Xiaoyun, Kommagani, Ramakrishna, Wang, Ting, Solnica-Krezel, Lilianna, Theunissen, Thorold W
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2020
Soggetti:
Stem Cells and Regenerative Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062471/
https://ncbi.nlm.nih.gov/pubmed/32048992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52504
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