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Mechanisms of gene regulation in human embryos and pluripotent stem cells

Pluripotent stem cells have broad utility in biomedical research and their molecular regulation has thus garnered substantial interest. While the principles that establish and regulate pluripotency have been well defined in the mouse, it has been difficult to extrapolate these insights to the human...

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Dettagli Bibliografici
Pubblicato in:Development
Autori principali: Theunissen, Thorold W., Jaenisch, Rudolf
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769625/
https://ncbi.nlm.nih.gov/pubmed/29254992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.157404
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