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Mechanisms of gene regulation in human embryos and pluripotent stem cells

Pluripotent stem cells have broad utility in biomedical research and their molecular regulation has thus garnered substantial interest. While the principles that establish and regulate pluripotency have been well defined in the mouse, it has been difficult to extrapolate these insights to the human...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Theunissen, Thorold W., Jaenisch, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769625/
https://ncbi.nlm.nih.gov/pubmed/29254992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.157404
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