Bisdemethoxycurcumin Inhibits Hepatocellular Carcinoma Proliferation Through Akt Inactivation via CYLD-Mediated Deubiquitination

BACKGROUND: Bisdemethoxycurcumin (BDMC), a stable bioactive ingredient in curcuminoids, is associated with various antitumor functions, such as proliferation inhibition, metastasis suppression and apoptosis induction, in many cancer types. However, the mechanism of BDMC in hepatocellular carcinoma (...

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Publicado en:Drug Des Devel Ther
Autores principales: Qiu, Chengjiang, Liu, Kairui, Zhang, Sheng, Gao, Simin, Chen, Weirun, Li, Dateng, Huang, Youxing
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove 2020
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062405/
https://ncbi.nlm.nih.gov/pubmed/32184568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S231814
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