CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6

Cilia are hair-like organelles extending from the cell surface with important sensory and motility functions. Ciliary defects can result in a wide range of human diseases known as ciliopathies. However, the molecular mechanisms controlling ciliogenesis remain poorly defined. Here we show that cylind...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Yang, Yunfan, Ran, Jie, Liu, Min, Li, Dengwen, Li, Yuanyuan, Shi, Xingjuan, Meng, Dan, Pan, Junmin, Ou, Guangshuo, Aneja, Ritu, Sun, Shao-Cong, Zhou, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220159/
https://ncbi.nlm.nih.gov/pubmed/25342559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.136
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