Transplantation-Induced Ischemia-Reperfusion Injury Modulates Antigen Presentation by Donor Renal CD11c(+)F4/80(+) Macrophages through IL-1R8 Regulation

BACKGROUND: In donor kidneys subjected to ischemia-reperfusion injury during kidney transplant, phagocytes coexpressing the F4/80 and CD11c molecules mediate proinflammatory responses and trigger adaptive immunity in transplantation through antigen presentation. After injury, however, resident renal...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Aiello, Sistiana, Podestà, Manuel Alfredo, Rodriguez-Ordonez, Pamela Y., Pezzuto, Francesca, Azzollini, Nadia, Solini, Samantha, Carrara, Camillo, Todeschini, Marta, Casiraghi, Federica, Noris, Marina, Remuzzi, Giuseppe, Benigni, Ariela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2020
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062225/
https://ncbi.nlm.nih.gov/pubmed/31988271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019080778
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