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Human polymorphisms in GSDMD alter the inflammatory response
Exomic studies have demonstrated that innate immune genes exhibit an even higher degree of variation than the majority of other gene families. However, the phenotypic implications of this genetic variation are not well understood, with effects ranging from hypomorphic to silent to hyperfunctioning....
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7062166/ https://ncbi.nlm.nih.gov/pubmed/31988247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010604 |
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