High-resolution crystal structures of two prototypical β- and γ-herpesviral nuclear egress complexes unravel the determinants of subfamily specificity

Herpesviruses uniquely express two essential nuclear egress-regulating proteins forming a heterodimeric basic structure of the nuclear egress complex (core NEC). These core NECs serve as a hexameric lattice-structured platform for capsid docking and recruit viral and cellular NEC-associated factors...

Full description

Saved in:
Bibliographic Details
Published in:J Biol Chem
Main Authors: Muller, Yves A., Häge, Sigrun, Alkhashrom, Sewar, Höllriegl, Tobias, Weigert, Sebastian, Dolles, Simon, Hof, Kerstin, Walzer, Sascha A., Egerer-Sieber, Claudia, Conrad, Marcus, Holst, Stephanie, Lösing, Josephine, Sonntag, Eric, Sticht, Heinrich, Eichler, Jutta, Marschall, Manfred
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2020
Subjects:
Molecular Bases of Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062154/
https://ncbi.nlm.nih.gov/pubmed/31980459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011546
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items