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Exploring the Human Cytomegalovirus Core Nuclear Egress Complex as a Novel Antiviral Target: A New Type of Small Molecule Inhibitors

Nuclear egress is an essential process in the replication of human cytomegalovirus (HCMV), as it enables the migration of newly formed viral capsids from the nucleus into the cytoplasm. Inhibition of the HCMV core nuclear egress complex (core NEC), composed of viral proteins pUL50 and pUL53, has bee...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Viruses
Hauptverfasser: Alkhashrom, Sewar, Kicuntod, Jintawee, Häge, Sigrun, Schweininger, Johannes, Muller, Yves A., Lischka, Peter, Marschall, Manfred, Eichler, Jutta
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998563/
https://ncbi.nlm.nih.gov/pubmed/33809234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13030471
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