Solid-phase combinatorial synthesis using microarrays of microcompartments with light-induced on-chip cell screening

The process of drug discovery includes individual synthesis and characterization of drug candidates, followed by a biological screening, which is separated from synthesis in space and time. This approach suffers from low throughput and associated high costs, which in turn lead to inefficiency in the...

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Bibliografiske detaljer
Udgivet i:	Mater Today Bio
Main Authors:	Rosenfeld, A., Brehm, M., Welle, A., Trouillet, V., Heissler, S., Benz, M., Levkin, P.A.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2019
Fag:	Full Length Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7061619/ https://ncbi.nlm.nih.gov/pubmed/32159150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mtbio.2019.100022
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Solid-phase combinatorial synthesis using microarrays of microcompartments with light-induced on-chip cell screening

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