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Solid-phase combinatorial synthesis using microarrays of microcompartments with light-induced on-chip cell screening

The process of drug discovery includes individual synthesis and characterization of drug candidates, followed by a biological screening, which is separated from synthesis in space and time. This approach suffers from low throughput and associated high costs, which in turn lead to inefficiency in the...

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Dades bibliogràfiques
Publicat a:Mater Today Bio
Autors principals: Rosenfeld, A., Brehm, M., Welle, A., Trouillet, V., Heissler, S., Benz, M., Levkin, P.A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061619/
https://ncbi.nlm.nih.gov/pubmed/32159150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mtbio.2019.100022
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