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Marrying chemistry with biology by combining on-chip solution-based combinatorial synthesis and cellular screening
Drug development often relies on high-throughput cell-based screening of large compound libraries. However, the lack of miniaturized and parallelized methodologies in chemistry as well as strict separation and incompatibility of the synthesis of bioactive compounds from their biological screenings m...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6599004/ https://ncbi.nlm.nih.gov/pubmed/31253767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10685-0 |
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