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Marrying chemistry with biology by combining on-chip solution-based combinatorial synthesis and cellular screening
Drug development often relies on high-throughput cell-based screening of large compound libraries. However, the lack of miniaturized and parallelized methodologies in chemistry as well as strict separation and incompatibility of the synthesis of bioactive compounds from their biological screenings m...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6599004/ https://ncbi.nlm.nih.gov/pubmed/31253767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10685-0 |
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