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A mechanism to minimize errors during non-homologous end joining
Enzymatic processing of DNA underlies all DNA repair, yet inappropriate DNA processing must be avoided. In vertebrates, double-strand breaks are repaired predominantly by non-homologous end-joining (NHEJ), which directly ligates DNA ends. NHEJ has the potential to be highly mutagenic because it empl...
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| Publicado en: | Mol Cell |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7060804/ https://ncbi.nlm.nih.gov/pubmed/31862156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.11.018 |
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