Individual Ion Mass Spectrometry Enhances the Sensitivity and Sequence Coverage of Top Down Mass Spectrometry

Charge detection mass spectrometry (CDMS) is mainly utilized to determine the mass of intact molecules. Previous applications of CDMS have determined the mass-to-charge ratio and charge of large polymers, DNA molecules, and native protein complexes, from which corresponding mass values could be assi...

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Publicado en:J Proteome Res
Main Authors: Kafader, Jared O., Durbin, Kenneth R., Melani, Rafael D., Des Soye, Benjamin J., Schachner, Luis F., Senko, Michael W., Compton, Philip D., Kelleher, Neil L.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060802/
https://ncbi.nlm.nih.gov/pubmed/32032494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.9b00797
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