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Isotopic Resolution of Protein Complexes up to 466 kDa Using Individual Ion Mass Spectrometry

Native mass spectrometry involves transferring large biomolecular complexes into the gas phase, enabling the characterization of their composition and stoichiometry. However, the overlap in distributions created by residual solvation, ionic adducts, and post-translational modifications creates a hig...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: McGee, John P., Melani, Rafael D., Yip, Ping F., Senko, Michael W., Compton, Philip D., Kafader, Jared O., Kelleher, Neil L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878367/
https://ncbi.nlm.nih.gov/pubmed/33322893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c03282
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