Late steps in bacterial translation initiation visualized using time-resolved cryo-EM

Bacterial translation initiation entails the tightly regulated joining of the 50S ribosomal subunit to an initiator transfer RNA (fMet-tRNA(fMet))-containing 30S ribosomal initiation complex (IC) to form a 70S IC that subsequently matures into a 70S elongation-competent complex (70S EC). Rapid and a...

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Bibliografiska uppgifter
I publikationen:Nature
Huvudupphovsmän: Kaledhonkar, Sandip, Fu, Ziao, Caban, Kelvin, Li, Wen, Chen, Bo, Sun, Ming, Gonzalez, Ruben L., Frank, Joachim
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060745/
https://ncbi.nlm.nih.gov/pubmed/31108498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1249-5
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