Structural dynamics of ribosome subunit association studied by mixing-spraying time-resolved cryo-EM

Ribosomal subunit association is a key checkpoint in translation initiation, but its structural dynamics are poorly understood. Here, we used a recently developed mixing-spraying, time-resolved, cryogenic electron microscopy (cryo-EM) method to study ribosomal subunit association in the sub-second t...

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Veröffentlicht in:Structure
Hauptverfasser: Chen, Bo, Kaledhonkar, Sandip, Sun, Ming, Shen, Bingxin, Lu, Zonghuan, Barnard, David, Lu, Toh-Ming, Gonzalez, Ruben L., Frank, Joachim
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456197/
https://ncbi.nlm.nih.gov/pubmed/26004440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.04.007
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