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Initial bridges between two ribosomal subunits are formed within 9.4 milliseconds, as studied by time-resolved cryo-EM

Association of the two ribosomal subunits during the process of translation initiation is a crucial step of protein synthesis. The two subunits (30S and 50S) of the bacterial 70S ribosome are held together by 12 dynamic bridges involving RNA–RNA, RNA–protein, and protein–protein interactions. The pr...

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Detalhes bibliográficos
Main Authors: Shaikh, Tanvir R., Yassin, Aymen S., Lu, Zonghuan, Barnard, David, Meng, Xing, Lu, Toh-Ming, Wagenknecht, Terence, Agrawal, Rajendra K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103372/
https://ncbi.nlm.nih.gov/pubmed/24958863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406744111
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