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ALDH1A3‐mTOR axis as a therapeutic target for anticancer drug‐tolerant persister cells in gastric cancer

Tumors consist of heterogeneous cell populations that contain cancer cell subpopulations with anticancer drug‐resistant properties called “persister” cells. While this early‐phase drug tolerance is known to be related to the stem cell‐like characteristic of persister cells, how the stem cell‐related...

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Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Kawakami, Ryuhei, Mashima, Tetsuo, Kawata, Naomi, Kumagai, Koshi, Migita, Toshiro, Sano, Takeshi, Mizunuma, Nobuyuki, Yamaguchi, Kensei, Seimiya, Hiroyuki
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060474/
https://ncbi.nlm.nih.gov/pubmed/31960523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14316
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