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DIEPOXYBUTANE INDUCES THE EXPRESSION OF A NOVEL p53-TARGET GENE XCL1 THAT MEDIATES APOPTOSIS IN EXPOSED HUMAN LYMPHOBLASTS.
Diepoxybutane (DEB) is the most potent active metabolite of the environmental chemical 1, 3-butadiene (BD). BD is a human carcinogen that exhibits multi-organ systems toxicity. Our previous studies demonstrated that XCL1 (X-C motif chemokine ligand 1) gene expression was up-regulated 3.3-fold in a p...
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| Publicado no: | J Biochem Mol Toxicol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7060116/ https://ncbi.nlm.nih.gov/pubmed/31953984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbt.22446 |
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