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Targeting survivin and p53 in pediatric acute lymphoblastic leukemia

Despite advances in treatment and outcomes for patients with pediatric acute lymphoblastic leukemia (ALL), there continue to be subsets of patients who are refractory to standard chemotherapy and hematopoietic stem cell transplant. Therefore, novel gene targets for therapy are needed to further adva...

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Bibliographic Details
Main Authors: Tyner, J W, Jemal, A M, Thayer, M, Druker, B J, Chang, B H
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364442/
https://ncbi.nlm.nih.gov/pubmed/21960246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2011.249
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