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Targeting survivin and p53 in pediatric acute lymphoblastic leukemia

Despite advances in treatment and outcomes for patients with pediatric acute lymphoblastic leukemia (ALL), there continue to be subsets of patients who are refractory to standard chemotherapy and hematopoietic stem cell transplant. Therefore, novel gene targets for therapy are needed to further adva...

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Autors principals: Tyner, J W, Jemal, A M, Thayer, M, Druker, B J, Chang, B H
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364442/
https://ncbi.nlm.nih.gov/pubmed/21960246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2011.249
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