Advanced paternal age directly impacts mouse embryonic placental imprinting

The placental epigenome plays a critical role in regulating mammalian growth and development. Alterations to placental methylation, often observed at imprinted genes, can lead to adverse pregnancy complications such as intrauterine growth restriction and preterm birth. Similar associations have been...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Denomme, Michelle M., Parks, Jason C., McCallie, Blair R., McCubbin, Nathan I., Schoolcraft, William B., Katz-Jaffe, Mandy G.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059926/
https://ncbi.nlm.nih.gov/pubmed/32142542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229904
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