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Epigenetic Dysregulation Observed in Monosomy Blastocysts Further Compromises Developmental Potential
Epigenetic mechanisms such as DNA methylation regulate genomic imprinting and account for the distinct non-equivalence of the parental genomes in the embryo. Chromosomal aneuploidy, a major cause of infertility, distorts this highly regulated disparity by the presence or absence of chromosomes. The...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4896457/ https://ncbi.nlm.nih.gov/pubmed/27271036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156980 |
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