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Hypomethylation and Genetic Instability in Monosomy Blastocysts May Contribute to Decreased Implantation Potential
DNA methylation is a key epigenetic mechanism responsible for gene regulation, chromatin remodeling, and genome stability, playing a fundamental role during embryonic development. The aim of this study was to determine if these epigenetic marks are associated with chromosomal aneuploidy in human bla...
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| Publicado en: | PLoS One |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4951028/ https://ncbi.nlm.nih.gov/pubmed/27434648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159507 |
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