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Advanced paternal age directly impacts mouse embryonic placental imprinting

The placental epigenome plays a critical role in regulating mammalian growth and development. Alterations to placental methylation, often observed at imprinted genes, can lead to adverse pregnancy complications such as intrauterine growth restriction and preterm birth. Similar associations have been...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Denomme, Michelle M., Parks, Jason C., McCallie, Blair R., McCubbin, Nathan I., Schoolcraft, William B., Katz-Jaffe, Mandy G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059926/
https://ncbi.nlm.nih.gov/pubmed/32142542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229904
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