Multivalent Polymer–Peptide Conjugates—A General Platform for Inhibiting Amyloid Beta Peptide Aggregation

Protein aggregation is implicated in multiple deposition diseases including Alzheimer’s Disease, which features the formation of toxic aggregates of amyloid beta (Aβ) peptides. Many inhibitors have been developed to impede or reverse Aβ aggregation. Multivalent inhibitors, however, have been largely...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Macro Lett
Prif Awduron: Jiang, Xing, Halmes, Abigail J., Licari, Giuseppe, Smith, John W., Song, Yang, Moore, Edwin G., Chen, Qian, Tajkhorshid, Emad, Rienstra, Chad M., Moore, Jeffrey S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059649/
https://ncbi.nlm.nih.gov/pubmed/32149017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmacrolett.9b00559
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