Multivalent Polymer–Peptide Conjugates—A General Platform for Inhibiting Amyloid Beta Peptide Aggregation

Protein aggregation is implicated in multiple deposition diseases including Alzheimer’s Disease, which features the formation of toxic aggregates of amyloid beta (Aβ) peptides. Many inhibitors have been developed to impede or reverse Aβ aggregation. Multivalent inhibitors, however, have been largely...

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Bibliografiske detaljer
Udgivet i:ACS Macro Lett
Main Authors: Jiang, Xing, Halmes, Abigail J., Licari, Giuseppe, Smith, John W., Song, Yang, Moore, Edwin G., Chen, Qian, Tajkhorshid, Emad, Rienstra, Chad M., Moore, Jeffrey S.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059649/
https://ncbi.nlm.nih.gov/pubmed/32149017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmacrolett.9b00559
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