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Inhibition of USP7 activity selectively eliminates senescent cells in part via restoration of p53 activity
The accumulation of senescent cells (SnCs) is a causal factor of various age‐related diseases as well as some of the side effects of chemotherapy. Pharmacological elimination of SnCs (senolysis) has the potential to be developed into novel therapeutic strategies to treat these diseases and pathologi...
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| Publicado no: | Aging Cell |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7059172/ https://ncbi.nlm.nih.gov/pubmed/32064756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13117 |
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