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Novel Alzheimer risk genes determine the microglia response to amyloid‐β but not to TAU pathology
Polygenic risk scores have identified that genetic variants without genome‐wide significance still add to the genetic risk of developing Alzheimer's disease (AD). Whether and how subthreshold risk loci translate into relevant disease pathways is unknown. We investigate here the involvement of A...
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| Pubblicato in: | EMBO Mol Med |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7059012/ https://ncbi.nlm.nih.gov/pubmed/31951107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201910606 |
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